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| Cinque,S.M.S.; Rocha,G.A.; Correa-Oliveira,R.; Soares,T.F.; Moura,S.B.; Rocha,A.M.C.; Nogueira,A.M.M.F.; Cabral,M.M.D.A.; Vieira,L.Q.; Martins-Filho,O.A.; Queiroz,D.M.M.. |
| Although Helicobacter heilmannii infection is less common than H. pylori infection in humans, it is considered to be of medical importance because of its association with gastritis, gastric ulcer, carcinoma, and mucosa-associated lymphoid tissue lymphoma of the stomach. However, there have been no studies evaluating the role of the Th cell response in H. heilmannii gastric infection. We evaluated the participation of pro-inflammatory and anti-inflammatory cytokines, IFN-gamma and IL-4, in H. heilmannii gastric infection in genetically IFN-gamma- or IL-4-deficient mice. The serum IFN-gamma and IL-4 concentrations were determined by ELISA. The gastric polymorphonuclear infiltrate was higher (P = 0.007) in H. heilmannii-positive than in H. heilmannii-negative... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Helicobacter heilmannii; Gastric mucosa inflammation; IFN-gamma-/- mice; IL-4-/- mice. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000200012 |
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